Clinical

Head and neck cancers are diverse and increasing in prevalence. Treatment usually consists of a combination of surgery, radiotherapy and chemotherapy; and increasingly immunotherapy. However, the results of treatment can have significant lasting effects. Implementation of new surgical techniques, improved radiotherapy and advanced high-resolution fusion imaging aim to reduce these effects. In addition, the Centre is actively engaged in a variety of novel cutting-edge scientific clinical trials that aim to deliver new therapies to improve patient outcomes.

Director: Professor Ben Panizza

Director, Otolaryngology – Head and Neck Surgery, Princess Alexandra Hospital

Clinical Trials

  • PATHOS – Post-operative adjuvant treatment for HPV-positive tumours
    • Cardiff University (UK)
  • QBio H08 – A Phase II, open label, single arm study to assess the efficacy of intratumoural tigilanol tiglate in various head and neck solid malignancies
    • QBiotics Group Limited (AU)
  • Decibel – Phase 1b Randomized Double-Blind Placebo-Controlled Multicenter Study to Evaluate the Safety Tolerability Pharmacokinetics Pharmacodynamics of Repeated Doses of DB-020 in PatientsReceivingCisplatin
    • Decibel Therapeutics Pty Ltd (AU)

Clinical Projects

  • PNS – Studying the Factors Involved in the Perineural Spread of Head and Neck Malignancy
    • QIMR Berghoffer Research Institute, University of Queensland, Children’s’ Medical Research Institute (ProCan)
  • PNI – A review of basal cell carcinoma (BCC) and squamous cell keratinocyte cancers exhibiting perineural invasion diagnosed pathologically in Queensland
    • QIMR Berghoffer Research Institute, University of Queensland
  • TMA – Tissue microarray analysis of oropharyngeal squamous cell carcinoma tumours
    • University of Queensland, Children’s’ Medical Research Institute (ProCan)
  • Sinonasal and Skull Base Malignancies Study
    • Memorial Sloan Kettering (US)
  • PORTHES-OC – Ascertaining the impact of adjuvant radiotherapy in early-stage, risk factor-positive oral cavity squamous cell carcinoma, and evaluating patterns of failure
    • University of Oklahoma (US)
  • EAC – External Auditory Canal Carcinoma
    • Radboud University (NL)
  • SNUCS – Outcomes of sinonasal undifferentiated carcinomas treated in a tertiary Australian hospital
  • Cutaneous Malignancy Extending to the Temporal Bone
    • University of Queensland
  • Vestibular Schwannoma